RNA Details
Disease Name
renal fibrosis
Tissue
kidney
RNA Symbol
circRNA_30032
RNA ID
RNA Type
circRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR;western blot;luciferase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
Title
CircRNA_30032 promotes renal fibrosis in unilateral ureteral obstruction model mice via miRNA-96-5p/HBEGF/KRAS axis
Year
2021
Function
"CircRNA_30032 mediated TGF-BETA1-induced and unilateral ureteral obstruction-induced renal fibrosis by sponging miR-96-5p and increasing the expression of profibrotic proteins, including HBEGF, KRAS, collagen I, collagen III and fibronectin."